AMG 706 / AMG706
AMG 706 is Amgen's first small molecule anti-cancer therapeutic candidate, which selectively inhibits multiple kinases involved in the formation of blood vessels. AMG 706 appeared to reduce vascular permeability and blood flow in human tumors in a Phase 1 trial. Early clinical data shows signs of tumor regression with promising preliminary safety data that allows for combination therapy. (from Amgen.com)
Phase I trials are underway at John Wayne Cancer Institute (Santa Monica, Ca.) and at M.D. Anderson Cancer Center (Houston, Texas)
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LINKS
Yahoo Groups Chat Site : Discussion forum for anyone interested in AMG 706 / AMG706
AMG 706 : Amgen's info page
AMG 706 : M.D. Anderson Cancer Center's Phase 1 Clinical Trial
AMG 706 : Phase II Clinical Trial - GIST patients
GSI : Gist Support International (Gastrointestinal Stromal Tumors) - current AMG 706 info is posted here.
AMG Abstract
: Released by Amgen in October 2004.
I am not a medical or health professional. Information in this site has been gathered from numerous sources and is for research purposes only. I do not guarantee the accuracy of any information in this site. Desmoplastic Small Round Cell Tumor www.DSRCT.com