Sarah Taylor Gibson  (Canada)

DSRCT Diagnosed 10/97 - Passed Away 7/17/00

http://users.uniserve.ca/~bggibson/sara/

Treatment Summary (from Sarah's web page)

Sara's chemotherapy was a version of the "P6" protocol. Note that each individual's oncologist will adjust based on the individual's health at the time of treatment and any new information.

Sara's finalized chemotherapy protocols:

"HD-VAC" (2 day treatment)

"HIPE" (High dose I... P... E...) (5 day treatment)

Vincristine Ifosfomide
Adriamycin Platin (cysplatin in Sara's case)
Cyclophosphamide Etoposide

Sara specifically had:

Oct 22, 1997 - high dose chemotherapy (VAC)

Nov 10, 1997 - high dose chemotherapy (HIPE)

Dec 2, 1997 - high dose chemotherapy (VAC)

Dec 29, 1997 - debulking surgery

Jan 12, 1998 - high dose chemotherapy (HIPE)

Feb 9, 1998 - high dose chemotherapy (VAC)

 followed by

High Dose Chemotherapy and Peripheral Stem Cell Replacement:

- a high dose chemotherapy (ifosphomide/ platin/ etoposide) and total body irridation (that has the side-effect of wiping out bone-marrow). The whole point of this protocol is to clean up any floating DSRCT cells that are left in the body. The aggresiveness of this treatment will wipe out Sara's bone marrow but Sara's bone marrow biopsy showed perfectly healthy bone marrow so there should not be any difficulty in getting the stem cells to graft back into Sara's bones.

March 6, 1998 - begining of High Dose Chemotherapy and Stem Cell Replacement

March 7, 1998 - high dose chemotherapy (VP16 - etoposide)

March 8 , 1998 - high dose chemotherapy (cyclophosphomide)

March 9 , 1998 - high dose chemotherapy (cyclophosphomide)

March 10 , 1998 - high dose chemotherapy (cyclophosphomide)

March 11 & 12, 1998 - 3 doses TBI (total body irridation)

March 13, 1998 - stem cell infussion

 After this point, Sara has had no more treatment except that her naturopath has provided to keep her immune system strong and some to attack/starve the cancer cells. There was no more treatment that the British Columbia Cancer Agency could safely give her. The high dose chemotherapy and the HD-chemo with Stem Cell Rescue were the best bet for treatment when Sara was diagnosed.

Since her recurrance there has been no treatment other than localized radiation for palliative purposes.

Sara's particular ("divergent") form of DSRCT has proven resistant to the chemotherapy and unfortunately radiation is limited due to presence of masses on the liver and spleen (which would not survive the high doses of radiation neccessary for a kill).

We both hope that as time passes there will be more possibilites for effective treatment BUT it is important to remember that this disease has different progression with each person and that there may be other treatment options. Ask your oncologist and if they don't know I would suggest contacting the specialists in this field for information: Dr. Kushner (at Memorial Sloan-Kettering in New York); Dr.s Miser and Sato (City of Hope - Los Angeles); and Sara's own oncologist Dr. Knowling (via your oncoligist contacting the British Columbia Cancer Agency - Vancouver B.C.).

 

 

 

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